Phenotypic consensus markers for plasma cell myeloma
نویسندگان
چکیده
منابع مشابه
Phenotypic consensus markers for plasma cell myeloma
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. http://dx.doi.org/10.5045/kjh.2012.47.4.239 The Korean Journal of Hematology Volume 47ᆞNumbe...
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Multiple myeloma (MM) is a B-cell malignancy characterized by the accumulation, primarily in bone marrow, of a clone of plasma cells. The nature of the stem cells feeding the tumoral compartment is still unknown. To investigate this special point, we have studied the phenotypes of nine well-known human myeloma cell lines (HMCLs) and compared them with those of normal lymphoblastoid cell lines (...
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We have recently shown that two-color analysis with fluorescein isothiocyanate (FITC)-anti-CD38 antibody could clearly distinguish myeloma cells (plasma cells) from other hematopoietic cells in the bone marrow. Myeloma cells (plasma cells) alone were located at CD38strong positive (++) fractions. To further distinguish normal plasma cells from mature myeloma cells phenotypically, we examined im...
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ژورنال
عنوان ژورنال: The Korean Journal of Hematology
سال: 2012
ISSN: 1738-7949,2092-9129
DOI: 10.5045/kjh.2012.47.4.239